Working as a powerful Nrf2 Activator, Protandim acts as a ‘master switch’ regulator to over 3000 genes, 500 of which are often referred to as “survival genes”.
What is Nfr2 & HOW Does It Help You
'Biohack' the Aging Code?
Nfr2 is a protein within our cells that modulates hundreds of cells that are involved in:
Synergistic Induction of Heme Oxygenase-1 by the Components of an Antioxidant Supplement Protandim® Free Radical Biology and Medicine (2009)
Abstract: Protandim® is a supplement formulated with the objective of combining multiple phytochemicals at low non-toxic doses to gain synergy for induction of endogenous antioxidant enzymes. All components together produced a strongly synergistic induction of around three to ninefold, greatly exceeding the sum of the parts, and strongly suggesting this may be an effective method for the induction of antioxidant enzymes.
Conclusion: Protandim® produces a 300% increase in the cellular production of glutathione. As a key antioxidant, glutathione plays critical roles in the regenesis of other antioxidants (vitamins C and E), liver detoxification and elimination, and tissue repair. Further, Protandim® was shown to be a Nrf2 Activator. Findings show nuclear translocation of Nrf2 to the Antioxidant Response Element sites of genes on the DNA. Nrf2 then “re-tunes” the associated genes to function optimally.
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